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Note: The chart below reflects the products currently sold by Searle in the United States. Detailed product information for use in the United States is available by clicking on the product name. This detailed product information is used by U.S. healthcare professionals when deciding when and how to prescribe these products. However, the information provided here is not a substitute for consulting with a healthcare professional. All questions about medical care and the effects of a product should be directed to a doctor or other healthcare professional.

cardiovascular | sleep | arthritis | women's health| FDA clearance now being sought


CARDIOVASCULAR

Aldactone®
(spironolactone)

Treatment of edema (swelling due to fluid retention, which is often associated with congestive heart failure and kidney failure) and hypertension (usually in combination with other drugs). Classification: diuretic.

Aldactazide®
(spironolactone/
hydrochlorothiazide)

Treatment of hypertension and edema. Classification: combination of two diuretics.

Calan®
Calan® SR
(verapamil hydrochloride)

Calan: Treatment of angina (chest pain), hypertension and certain arrhythmias (irregular heart beat). Classification: calcium channel blocker.

Calan SR: Treatment of hypertension, with a sustained-relief formulation that allows once-a-day dosing. Classification: long-acting calcium channel blocker.

Covera-HS
(verapamil hydrochloride)

Treatment of hypertension and angina. COER-24™ delivery system is designed to align treatment with the body's natural circadian rhythms. Classification: long-acting calcium channel blocker.

Kerlone®
(betaxolol hydrochloride)

Treatment of hypertension. Classification: beta blocker.

Norpace®
Norpace® CR

(disopyramide phosphate)

Treatment of documented, life-threatening ventricular arrhythmias (irregular heart beat). Controlled-release (CR) formulation allows twice-a-day dosing.

Slow-Mag®
(magnesium chloride)

Dietary supplement that replenishes magnesium levels in the body. Available without a prescription.



SLEEP

Ambien®
(zolpidem tartrate) CIV

Short-term treatment of insomnia.




ARTHRITIS

Daypro®
(oxaprozin)

Treatment of the signs and symptoms of osteoarthritis and rheumatoid arthritis. Classification: nonsteroidal anti-inflammatory drug (NSAID).

Cytotec®
(misoprostol)
Prevention of gastric ulcers caused by use of nonsteroidal anti-inflammatory drugs (NSAIDs), the most common medications for treating arthritis symptoms.



WOMEN'S HEALTH

Flagyl®
(metronidazole)

Flagyl® 375
(metronidazole capsules)

Treatment of certain anaerobic bacterial infections, including trichomonas vaginalis, a common gynecologic infection. 375 mg dosage form allows medication to be taken twice a day rather than three times.

Demulen®
(ethynodiol diacetate with ethinyl estradiol)

Tri-Norinyl®
Norinyl® 1 + 35
Brevicon®
(norethindrone and ethinyl estradiol)

Norinyl® 1 + 50
(norethindrone and mestranol)

Nor-QD®
(norethindrone)

Oral contraceptives for the prevention of pregnancy.

Synarel®
(nafarelin acetate)

Nasal spray for the treatment of endometriosis (a growth of tissue outside of the uterus), which often causes pain and infertility.



FDA CLEARANCE NOW BEING SOUGHT

Arthrotec®
(diclofenac/misoprostol)

Treatment of osteoarthritis and adult rheumatoid arthritis. Combines diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), with misoprostol, which helps protect against NSAID-induced gastric ulcers. New drug application filed with U.S. Food and Drug Administration December 1995.





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